Tocris NS 3763
Selective non-competitive kainate antagonist; selective for GLUK5
Manufacturer: Tocris 2187/50
DescriptionSelective non-competitive kainate receptor antagonist; displays selectivity for GLUK5 subunit-containing receptors (IC50 values are 1.6 and > 30µM for homomeric GLUK5 and GLUK6 receptors respectively). Has minimal activity at AMPA and NMDA receptors (IC50> 30µM).
- Chemical Name: 4,6-Bis(benzoylamino)-1,3-benzenedicarboxylic acid
- Formula: C22H16N2O6
- CAS Number: 70553-45-6
- Solubility: Soluble to 25mM in DMSO
- Purity: >99
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