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NS 6180, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
353262-04-1
C16H12F3NOS
323.333
ZUIJXKLTUFCDGO-UHFFFAOYSA-N
4-3-trifluoromethyl benzyl-2h-benzo b 1,4 thiazin-3 4h-one,4-3-trifluoromethyl phenyl methyl-1,4-benzothiazin-3-one,4-3-trifluoromethyl phenyl methyl-2h-1,4-benzothiazin-3-one,4-3-trifluoromethyl phenyl methyl-2h-1,4-benzothiazin-3 4h-one,4-3-trifluoromethyl phenyl methyl-3,4-dihydro-2h-1,4-benzothiazin-3-one
11837221
4-[[3-(trifluoromethyl)phenyl]methyl]-1,4-benzothiazin-3-one
C1C(=O)N(C2=CC=CC=C2S1)CC3=CC(=CC=C3)C(F)(F)F
This item is not returnable. View return policy
353262-04-1
C16H12F3NOS
323.333
ZUIJXKLTUFCDGO-UHFFFAOYSA-N
4-3-trifluoromethyl benzyl-2h-benzo b 1,4 thiazin-3 4h-one,4-3-trifluoromethyl phenyl methyl-1,4-benzothiazin-3-one,4-3-trifluoromethyl phenyl methyl-2h-1,4-benzothiazin-3-one,4-3-trifluoromethyl phenyl methyl-2h-1,4-benzothiazin-3 4h-one,4-3-trifluoromethyl phenyl methyl-3,4-dihydro-2h-1,4-benzothiazin-3-one
11837221
4-[[3-(trifluoromethyl)phenyl]methyl]-1,4-benzothiazin-3-one
C1C(=O)N(C2=CC=CC=C2S1)CC3=CC(=CC=C3)C(F)(F)F

Potent KCa3.1 channel blocker

Potent KCa3.1 channel blocker (IC50 values are 9, 14 and 15 nM for rat, human and mouse erythrocyte KCa3.1 channels respectively). Exhibits ∽ 50% inhibition of KCa1.1, KV1.3, and KV11.1 channels, noradrenaline and dopamine transporters, L-type Ca2+ channels and melatonin receptors at a concentration of 10 μM. Potently inhibits IL-2 and IFN-γ production in rat lymphocytes (IC50 ∽ 50 nM); reduces DBNS-induced experimental colitis in rats.
Quantity 10mg
Formula Weight 323.33
Percent Purity >99%
Chemical Name or Material NS 6180

Recommended Storage : Store at +4°C