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NS 6180, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Potent KCa3.1 channel blocker (IC50 values are 9, 14 and 15 nM for rat, human and mouse erythrocyte KCa3.1 channels respectively). Exhibits ∽ 50% inhibition of KCa1.1, KV1.3, and KV11.1 channels, noradrenaline and dopamine transporters, L-type Ca2+ channels and melatonin receptors at a concentration of 10 μM. Potently inhibits IL-2 and IFN-γ production in rat lymphocytes (IC50 ∽ 50 nM); reduces DBNS-induced experimental colitis in rats.
Specifications
Quantity | 10 mg |
Formula Weight | 323.33 |
Percent Purity | >99% |
Chemical Name or Material | NS 6180 |
Safety and Handling
Recommended Storage | Store at +4°C |
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