Tocris™ NSC 146109 hydrochloride

Cell-permeable, genotype-selective antitumor agent; activates p53-dependent transcription

Manufacturer: Tocris™ 2185/50

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Catalog No. 21-855-0R

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For Research Use Only


    Specifications

    Product Type NSC 146109 hydrochloride
    Inhibitors NSC 146109 hydrochloride
    Purity >99
    Molecular Weight 316.85
    Quantity 50mg

    Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.

    • Chemical Name: (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride
    • Formula: C17H16N2S.HCl
    • CAS Number: 59474-01-0
    • Solubility: Soluble to 10mM in ethanol and to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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