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Tocris™ NSC 23766

Selective inhibitor of Rac1-GEF interaction; antioncogenic

Manufacturer:  Tocris™ 2161/10

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Catalog No. 21-611-0R


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Disclaimers:

For Research Use Only


Specifications

Description

Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50µM) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotyes in prostate cancer cells.
  • Chemical Name: N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
  • Formula: C24H35N7.3HCl
  • CAS Number: 1177865-17-6
  • Solubility: Soluble to 100mM in water and to 100mM in DMSO
  • Purity: >99
Description & Specifications

Specifications

NSC 23766
>96
10mg
NSC 23766
530.97
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