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Tocris Bioscience™ NSC 319726

Reactivator of mutant p53

Manufacturer:  Tocris Bioscience™ 5065/10

Catalog No. 50-651-0RD


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Description

Description

  • Restores wild type p53 structure and function to the p53R175 mutant
  • Inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM)
  • Also inhibits growth of xenograft tumors expressing the p53R175 mutation in vivo
Specifications

Specifications

1-Azetidinecarbothioic acid [1-(2-pyridinyl)ethylidene]hydrazide
71555-25-4
234.32
0.98
C11H14N4S
10 mg
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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