Tocris Bioscience NSC 319726
Reactivator of mutant p53
Manufacturer: Tocris Bioscience 5065/50
DescriptionReactivator of mutant p53. Restores wild type p53 structure and function to the p53R175 mutant. Inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM). Also inhibits growth of xenograft tumors expressing the p53R175 mutation in vivo.
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