Tocris NSC 624206
Ubiquitin-activating enzyme (E1) inhibitor
Manufacturer: Tocris 4993/10
DescriptionUbiquitin-activating enzyme (E1) inhibitor; prevents tumour suppressor protein p27 ubiquitination in vitro. Blocks the ubiquitin-thioester formation step of the E1 activation reaction, but displays no effect on ubiquitin adenylation.
- Chemical Name: N-[2-[[(4-Chlorophenyl)methyl]dithio]ethyl]-1-decanamine hydrochloride
- Formula: C19H32ClNS2.HCl
- CAS Number: 13116-77-3
- Solubility: Soluble to 50mM in DMSO and to 20mM in ethanol
- Purity: >98
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