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NSC 687852, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
1009817-63-3
C22H17N3O6
419.393
GFARQYQBWJLZMW-JYFOCSDGSA-N
b-ap15,3e,5e-1-acryloyl-3,5-bis 4-nitrobenzylidene piperidin-4-one,3e,5e-3,5-bis 4-nitrophenyl methylidene-1-prop-2-enoylpiperidin-4-one,3e,5e-3,5-bis 4-nitrophenyl methylidene-1-prop-2-enoyl piperidin-4-one,b-ap-15,1-acryloyl-3,5-bis e-4-nitrobenzylidene piperidine-4-one,3,5-bis 4-nitrophenyl methylene-1-1-oxo-2-propene-1-yl-4-piperidone,4-piperidinone,5-bis 4-nitrophenyl methylene-1-1-oxo-2-propenyl,n-3-2,3-dihydro-2-oxo-3-1h-pyrrol-2-ylmethylene-1h-indol-6-yl amino-4-methylphenyl-n'-2-fluoro-5-trifluoromethyl phenyl ure a
5351435
(3E,5E)-3,5-bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one
C=CC(=O)N1CC(=CC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(=CC3=CC=C(C=C3)[N+](=O)[O-])C1
This item is not returnable. View return policy
1009817-63-3
C22H17N3O6
419.393
GFARQYQBWJLZMW-JYFOCSDGSA-N
b-ap15,3e,5e-1-acryloyl-3,5-bis 4-nitrobenzylidene piperidin-4-one,3e,5e-3,5-bis 4-nitrophenyl methylidene-1-prop-2-enoylpiperidin-4-one,3e,5e-3,5-bis 4-nitrophenyl methylidene-1-prop-2-enoyl piperidin-4-one,b-ap-15,1-acryloyl-3,5-bis e-4-nitrobenzylidene piperidine-4-one,3,5-bis 4-nitrophenyl methylene-1-1-oxo-2-propene-1-yl-4-piperidone,4-piperidinone,5-bis 4-nitrophenyl methylene-1-1-oxo-2-propenyl,n-3-2,3-dihydro-2-oxo-3-1h-pyrrol-2-ylmethylene-1h-indol-6-yl amino-4-methylphenyl-n'-2-fluoro-5-trifluoromethyl phenyl ure a
5351435
(3E,5E)-3,5-bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one
C=CC(=O)N1CC(=CC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(=CC3=CC=C(C=C3)[N+](=O)[O-])C1

Inhibitor of UCHL5 and USP14

Inhibitor of 19S regulatory particle associated deubiquitinating enzymes (DUBs), UCHL5 and USP14. Shows minimal inhibition of UCHL-1, UCHL-3, USP2, USP7, USP, BAP1 and proteasome activity. Induces apoptosis by cathepsin D-dependent caspase-cleavage (IC50 = 0.5 μM). Displays antitumor activity in vivo.

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Quantity 10mg
Formula Weight 419.39
Percent Purity >97%
Chemical Name or Material NSC 687852

Recommended Storage : Store at +4°C