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NSC 74859, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
NSC 74859 selectively inhibits STAT3 DNA-binding activity in vitro (IC50 values are 86, 160, and >300 μM for STAT3-STAT3, STAT1-STAT3 and STAT1-STAT1 DNA-binding activity respectively). NSC 74859 blocks growth and induces apoptosis preferentially in tumor cells that contain persistently active STAT3 in vitro and arrests tumor growth in a murine xenograft model in vivo.
Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 365.36 |
Percent Purity | >98% |
Chemical Name or Material | NSC 74859 |
Safety and Handling
Recommended Storage | Store at -20°C |
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