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NSE2 Mouse anti-Human, Clone: OTI4A2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525224

Catalog No. PIMA525224


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Description

Description

MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.
Specifications

Specifications

NSE2
Monoclonal
0.49 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q96MF7
C8orf36, MMS21, NSE2; E3 SUMO-protein ligase NSE2; MMS21 homolog; hMMS21; methyl methanesulfonate sensitivity gene 21; non-SMC element 2 homolog; non-structural maintece of chromosomes element 2 homolog
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
286053
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI4A2
Unconjugated
NSMCE2
Liquid
NSMCE2
Full length human recombit protein of NSMCE2 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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