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NT5E Mouse anti-Human, Clone: 4G6E3, Abnova™

Mouse monoclonal antibody raised against partial recombinant human NT5E.

Manufacturer:  Abnova Corporation MAB12266

Catalog No. 89-934-708


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Description

Description

Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.[supplied by OMIM]

Specifications

Specifications

NT5E
4G6E3
Mouse monoclonal antibody raised against partial recombinant human NT5E.
In PBS (0.05% sodium azide)
CD73/E5NT/NT/NT5/NTE/eN/eNT
Mouse
IgG1
RUO
Primary
4907
ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
ELISA (1:10000) Flow Cytometry (1:200-1:400) Immunohistochemistry (1:200-1:1000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
Liquid
NT5E
Recombinant protein corresponding to amino acids 30-250 of human TIE1.
100 ug
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
SDS
Documents
Product Certifications
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