NT5E Mouse anti-Human, Clone: 4G6E3, Abnova™
Mouse monoclonal antibody raised against partial recombinant human NT5E.
Manufacturer: Abnova Corporation MAB12266
Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 22.214.171.124) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.[supplied by OMIM]
|Mouse monoclonal antibody raised against partial recombinant human NT5E.|
|In PBS (0.05% sodium azide)|
|ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot|
|ELISA (1:10000) Flow Cytometry (1:200-1:400) Immunohistochemistry (1:200-1:1000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to amino acids 30-250 of human TIE1.|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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