NTHL1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 149181AP
DescriptionOxygen radicals damage chromosonal DNA causing cell death and inducing mutations. Although a major focus of oxidatively damaged DNA has centered on the repair of 8-oxo-G, a number of other damaged DNA sites are created by free-radical attack on DNA. The human NTH1 repair protein is one enzyme that has been shown to act on a large number of these other oxidatively damaged DNA sites.A homologue of E. coli Endonuclease III, NTH is a DNA glycosylase with apurinic/apyrimidinic lyase activity. The NTH protein has broad substrate specificity, including numerous ring saturation and fragmentation products of pyrimidines. Research indicates NTH plays a crucial role in removal of oxidative base lesions in mitochondrial DNA.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|NTH1, NTHL1, OCTS3|
|18207, 29541, 4913|
|Immunoprecipitation, Western Blot|
|NTHL1 Fusion Protein Ag6734|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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