Epredia™ Lab Vision™ Nucleophosmin (NPM) Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Take advantage of a quality product that delivers accurate results with the Epredia™ Nucleophosmin (NPM) Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS1849R1

Catalog No. MS1849R1

Description

Nucleophosmin (NPM)/B23/numatrin is a phosphoprotein associated with cell nucleoli. Treatment of cells with cytotoxic drugs may make nucleophosmin enter nucleoplasm. It is reported that nucleophosmin shuttles continuously between cytoplasm and nucleoli to carry newly synthesized ribosomal proteins into nucleoli. NPM-ALK is a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in anaplastic large cell lymphoma. In acute promyelocytic leukemia NPM gene is fused to RARalpha gene in (5;17) (q33;q12) transition.

Host Species: Mouse

Clone: NA24

Isotype: IgG/κ

Species Reactivity: Human. Others not known.

Epitope: N-terminal

Immunogen: GST fusion protein containing the N-terminal part of nucleophosmin fused to 14aa of ALK protein

Molecular Weight: 38kDa

Positive Control: Tonsil

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Nucleophosmin (NPM) Ab-1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Human
• Isotype: IgG κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: NA24
• Formulation: Ready-to-use for IHC (UVLP)
• Immunogen: GST fusion protein containing the N-terminal part of nucleophosmin fused to 14 aa of ALK protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Prediluted