NUP50 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 207981AP
DescriptionThe nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|O08587, Q9JIH2, Q9UKX7|
|50 kDa nucleoporin, nucleoporin 50kDa, Nucleoporin Nup50, NUP50|
|10762, 18141, 25497|
|NUP50 Fusion Protein Ag14710|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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