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Alfa Aesar™ O-Benzylphospho-N-Fmoc-L-serine, 95%

Manufacturer:  Alfa Aesar™ H5216803

Quantity 1g

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Catalog No. AAH5216803


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Specifications

Description

Applications
It can be applied in the synthesis of phosphopeptides. This derivative can be introduced using standard activation methods, such as PyBOP and TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods. β-piperidinylalanine formation has been shown to occur during Fmoc deprotection of N-terminal Ser(PO(OBzl)OH), particularly under microwave conditions. This side reaction can be eliminated by using cyclohexylamine or DBU just for this Fmoc deprotection step .

Solubility
Slightly soluble in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Description & Specifications

Chemical Identifiers

158171-14-3
497.44
7060483
O-Benzylphospho-N-Fmoc-L-serine
C25H24NO8P
MFCD00797869
Fmoc-Ser(PO3BzlH)-OH

Specifications

158171-14-3
497.44
7060483
1g
95%
C25H24NO8P
MFCD00797869
Fmoc-Ser(PO3BzlH)-OH
O-Benzylphospho-N-Fmoc-L-serine
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