Alfa Aesar™ O-Benzylphospho-N-Fmoc-L-serine, 95%

Manufacturer: Alfa Aesar™ H5216803

Quantity 1g

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Catalog No. AAH5216803

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    Chemical Identifiers

    CAS 158171-14-3
    Molecular Formula C25H24NO8P
    Formula Weight 497.44g/mol
    MDL Number MFCD00797869
    Beilstein 7060483
    Synonym Fmoc-Ser(PO3BzlH)-OH
    Chemical Name or Material O-Benzylphospho-N-Fmoc-L-serine

    Specifications

    Quantity 1g,1g
    CAS 158171-14-3
    Molecular Formula C25H24NO8P
    Formula Weight 497.44g/mol
    MDL Number MFCD00797869
    Beilstein 7060483
    Synonym Fmoc-Ser(PO3BzlH)-OH
    Chemical Name or Material O-Benzylphospho-N-Fmoc-L-serine
    Assay 95%

    Description

    Applications
    It can be applied in the synthesis of phosphopeptides. This derivative can be introduced using standard activation methods, such as PyBOP and TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods. β-piperidinylalanine formation has been shown to occur during Fmoc deprotection of N-terminal Ser(PO(OBzl)OH), particularly under microwave conditions. This side reaction can be eliminated by using cyclohexylamine or DBU just for this Fmoc deprotection step .

    Solubility
    Slightly soluble in water.

    Notes
    Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

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