Invitrogen™ OAS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550246

Catalog No. PA550246

Description

The antibody detects endogenous levels of total OAS2 protein.

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: OAS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OAS2
• Gene Alias: (2-5')oligo(A) synthase 2; (2'-5')oligo(A) synthetase 2; 2',5'-oligoadenylate synthetase-like 11; 2,5-oligoadenylate synthetase-like 11; 2'-5' oligoadenylate synthetase 2; 2'-5' oligoadenylate synthetase-like 11; 2-5A synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; A synthetase 2; MGC78578; Oas2; Oasl11; p69 OAS / p71 OAS; p69OAS / p71OAS
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 246728, 4939
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.9 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: E9Q9A9, P29728
• Gene Symbols: OAS2
• Immunogen: Fusion protein corresponding to a region derived from internal residues of human 2'-5'-oligoadenylate synthetase 2, 69/71kDa.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG