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OAS2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550246

Catalog No. PA550246


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Description

Description

The antibody detects endogenous levels of total OAS2 protein.

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2 ft.-specific nucleotidyl transfer reactions to synthesize 2 ft.,5 ft.-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Specifications

Specifications

OAS2
Polyclonal
Unconjugated
OAS2
Liquid
OAS2
Fusion protein corresponding to a region derived from internal residues of human 2′-5′-oligoadenylate synthetase 2, 69/71kDa
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
0.6 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P29728, E9Q9A9
MGC78578, p69 OAS / p71 OAS,p69OAS / p71OAS
Rabbit
IgG
100 μL
-20°C
Primary
246728, 4939
Documents
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