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OAS2 Mouse anti-Human, Clone: OTI5E1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526557

Catalog No. PIMA526557


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Description

Description

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2 ft.-specific nucleotidyl transfer reactions to synthesize 2 ft.,5 ft.-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Specifications

Specifications

OAS2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P29728
2′-5′-oligoadenylate synthetase 2 69/71kDa; ; 2′-5′oligo; A synthetase 2; 2′-5′-oligoadenylate synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4939
Immunohistochemistry (Paraffin), Western Blot
OTI5E1
Unconjugated
OAS2
Liquid
OAS2
Human recombit protein fragment corresponding to amino acids 60-335 of OAS2 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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