OAS2 Mouse anti-Human, Clone: OTI5E1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526557
DescriptionThis gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2 ft.-specific nucleotidyl transfer reactions to synthesize 2 ft.,5 ft.-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|2′-5′-oligoadenylate synthetase 2 69/71kDa; ; 2′-5′oligo; A synthetase 2; 2′-5′-oligoadenylate synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 60-335 of OAS2 produced in E.coli|
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