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OBFC2B Mouse anti-Human, Clone: OTI1E11, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA504022

Catalog No. 50-167-4795


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Description

Description

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintece of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
Specifications

Specifications

OBFC2B
Monoclonal
0.45 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9BQ15
OBFC2B, SOSS-B1, SSB1, hSSB1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
79035
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI1E11
Unconjugated
NABP2
Liquid
NABP2
Full length human recombit protein of human OBFC2B produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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