OBFC2B Mouse anti-Human, Clone: OTI1E11, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA504022
DescriptionComponent of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintece of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|OBFC2B, SOSS-B1, SSB1, hSSB1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of human OBFC2B produced in HEK293T cell.|
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