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OBFC2B Mouse anti-Human, Clone: OTI1E11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525801

Catalog No. PIMA525801


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Description

Description

Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintece of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
Specifications

Specifications

OBFC2B
Monoclonal
0.45 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9BQ15
SOSS complex subunit B1; Nucleic acid-binding protein 2; Oligonucleotide/oligosaccharide-binding fold-containing protein 2B; Sensor of single-strand DNA complex subunit B1; Sensor of ssDNA subunit B1; SOSS-B1; Single-stranded DNA-binding protein 1; hSSB1; NABP2; OBFC2B; SSB1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
79035
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI1E11
Unconjugated
NABP2
Liquid
NABP2
Full length human recombit protein of OBFC2B produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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