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OCRL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 176951AP

Catalog No. 50-173-1726


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Description

Description

This antibody is specific to OCRL.

The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. OCRL1 is a type II 5-phosphatase that is mutated in the oculocerebrorenal syndrome of Lowe (OCRL). OCRL is a rare X-linked disorder that is characterized in part by congenital cataracts, mental retardation, muscular hypotonia and renal tubular dysfunction.OCRL1 has a high affinity for phosphatidylinositol 4,5-bisphosphate as well as inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate as substrates. OCRL1 is localized to the Golgi complex and is thought to be part of the trans-Golgi network (TGN), which suggests that OCRL1 plays a role in protein sorting and trafficking within the cell.
Specifications

Specifications

OCRL
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
D3ZGS3, Q01968, Q6NVF0
INPP5F, LOCR, OCRL, OCRL1
Rabbit
IgG
150 μL
-20°C
Primary
317576, 320634, 4952
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
OCRL
Liquid
Ocrl
OCRL Fusion Protein Ag11900
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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