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Oct-4 Rabbit anti-Human, Mouse, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $546.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen Oct-4
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-2623 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
39812
10 μL
Each for $135.30
Add to cart
 
50-199-2622 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39811
100 μL
Each for $546.00
Add to cart
 
Description

Description

POU5F1, also commonly known as Oct-4, is a maternally expressed octamer-binding protein that was the first transcription factor described for the early stages of development. The role of POU5F1 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing POU5F1, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
Specifications

Specifications

Polyclonal
Primary
Oct-4
Unconjugated
SDS
Product Certifications
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