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Tocris Bioscience™ OF 1
Selective BRPF1B and BRPF2 inhibitor
Supplier: Tocris Bioscience™ 5289/10
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Description
OF 1 is a selective BRPF1B and BRPF2 bromodomain inhibitor (Kd values are 100 and 500 nM respectively). Exhibits 39-fold selectivity for BRPF1B and BRPF2 over BRD4. Accelerates FRAP recovery at 5 μM in a BRPF2 FRAP assay. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.Specifications
| 98% | |
| 919973-83-4 | |
| 10 mg | |
| M.W. (Observed): 440.31 |
| 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1 H-benzimidazol-5-yl)-2-methylbenzenesulfonamide | |
| 4°C | |
| OF 1 | |
| OF 1 |
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