Invitrogen™ OLFM1 Monoclonal Antibody (2G12-1B3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA521044

Catalog No. PIMA521044

Description

Peptide Sequence: MPGRWRWQRD MHPARKLLSL LFLILMGTEL TQNKRENKAE KMGGPESERK TTGEKTLNEL PLFCLEAHAG SLALPRMCSP NPNPAVGLCR PAYPQSPSPG AAQTISQSLL ERFCMASRRE VFLAPGRPGG GWWLCTVAGQ MHSFMCTHTH THAHTGEQIP AEKSQPGPD.

The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).

Specifications

• Antigen: OLFM1
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q99784
• Gene Symbols: OLFM1
• Immunogen: OLFM1 (AAH00189, 1 a.a. ~ 169 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA
• Clone: 2G12-1B3
• Conjugate: Unconjugated
• Gene: OLFM1
• Gene Alias: 1B426B; AMY; AW742568; D2Sut1e; neuroblastoma protein; neuronal olfactomedin-related ER localized protein; Noe1; Noel; Noel1; Noelin; Noelin 1; Noelin 2; NOELIN1; OlfA; olfactomedin 1; olfactomedin related ER localized protein; olfactomedin-1; OLFM1; Pancortin; pancortin 1; Pancortin 1-4; Pancortin3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10439
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid