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OLFM3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550866

Catalog No. PA550866


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Description

Description

The antibody detects endogenous levels of total OLFM3 protein.

OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
Specifications

Specifications

OLFM3
Polyclonal
Unconjugated
OLFM3
Liquid
OLFM3
Fusion protein corresponding to residues near the C terminal of human olfactomedin 3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1.1 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q96PB7, P63056
NOE3
Rabbit
IgG
100 μL
-20°C
Primary
118427, 229759
Documents
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