Invitrogen™ OLFM4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532955

Catalog No. PIPA532955

Description

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Dog (100%) Gibbon, Monkey, Panda (93%) Marmoset, Bat (87%) Hamster, Rabbit, Pig (80%).

OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.

Specifications

• Antigen: OLFM4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OLFM4
• Gene Alias: Antiapoptotic protein GW112; bA209J19.1; GC1; G-CSF-stimulated clone 1 protein; Gm296; Gm913; GW112; hGC-1; hOLfD; olfactomedin 4; olfactomedin-4; OlfD; OLFM4; OLM4; pPD4; PU.1 difference product 4; UNQ362; UNQ362/PRO698
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10562, 485470
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q6UX06
• Gene Symbols: OLFM4
• Immunogen: Synthetic 15 amino acid peptide from internal region of human OLFM4.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Canine
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov