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ONO 4817, Tocris Bioscience™

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Quantity:
10 mg
This item is not returnable. View return policy
223472-31-9
C22H28N2O6
416.474
HDWWQELUBWGQGA-WMZOPIPTSA-N
mmp inhibitor v, d0w8qh, ono-mi1-335, n-hydroxy-2 s-methyl-5-ethoxymethoxy-4 s-n-4-phenoxyphenylcarbonyl amino pentanamide, n-1s,3s-1-ethoxymethoxy methyl-4-hydroxyamino-3-methyl-4-oxobutyl-4-phenoxybenzamide, n-2s,4s-1-ethoxymethoxy-5-hydroxyamino-4-methyl-5-oxopentan-2-yl-4-phenoxy benzamide
9888141
N-[(2S,4S)-1-(ethoxymethoxy)-5-(hydroxyamino)-4-methyl-5-oxopentan-2-yl]-4-phenoxybenzamide
CCOCOCC(CC(C)C(=O)NO)NC(=O)C1=CC=C(C=C1)OC2=CC=CC=C2
This item is not returnable. View return policy
223472-31-9
C22H28N2O6
416.474
HDWWQELUBWGQGA-WMZOPIPTSA-N
mmp inhibitor v, d0w8qh, ono-mi1-335, n-hydroxy-2 s-methyl-5-ethoxymethoxy-4 s-n-4-phenoxyphenylcarbonyl amino pentanamide, n-1s,3s-1-ethoxymethoxy methyl-4-hydroxyamino-3-methyl-4-oxobutyl-4-phenoxybenzamide, n-2s,4s-1-ethoxymethoxy-5-hydroxyamino-4-methyl-5-oxopentan-2-yl-4-phenoxy benzamide
9888141
N-[(2S,4S)-1-(ethoxymethoxy)-5-(hydroxyamino)-4-methyl-5-oxopentan-2-yl]-4-phenoxybenzamide
CCOCOCC(CC(C)C(=O)NO)NC(=O)C1=CC=C(C=C1)OC2=CC=CC=C2

Description

Broad spectrum MMP inhibitor

Broad spectrum MMP inhibitor; Ki values are 0.45, 0.73, 1.1, 1.1, 2.1, 42 and 2500 nM for MMP-12, MMP-2, MMP-8, MMP-13, MMP-9, MMP-3 and MMP-7 respectively and IC50 = 1600 nM for MMP-1). Displays no activity at other proteases up to a concentration of 100 μM. Exhibits antiangiogenic and anti-invasive properties on lung metastasis of murine renal cell carcinoma.
Quantity 10 mg
Formula Weight 416.47
Percent Purity >99%
Chemical Name or Material ONO 4817

Safety and Handling

Recommended Storage : Store at Room Temperature

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