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Tocris Bioscience™ OptoBI-1

Photoswitchable TRPC3/6/7 agonist

Manufacturer:  Tocris Bioscience™ 7013/50

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Catalog No. 70-135-0


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Description

Description

OptoBI-1 is a photoswitchable TRPC3/6/7 agonist (EC50 for active cis-form ∽0.1 μM at TRPC3). Switches conformation from trans to cis at 365 nm and cis to trans at 430 nm. Returns to trans conformation in the dark after ∽ 50 minutes. No effect observed on TRPC4 or 5. Rapidly changes TRPC3 conductance and inhibits neuronal firing in cis-state.
Specifications

Specifications

1-[1-[4-[4-[(4-Butylphenyl)diazenyl]phenyl]butanoyl]piperidin-4-yl]-1,3-dihydro-2H-benzo[d]imidazol-2-one
C32H37N5O2
98%
50 mg
SDS
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