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Org 24598, >98%, Tocris Bioscience™

Catalog Number p-7121266
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Quantity:
10 mg
50 mg
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372198-97-5
C19H20F3NO3
367.368
KZWQAWBTWNPFPW-QGZVFWFLSA-N
2-methyl-3r-3-phenyl-3-4-trifluoromethyl phenoxy propyl amino acetic acid, d00lnk, n-methyl-n-3r-3-phenyl-3-4-trifluoromethyl phenoxy propyl-glycine, methyl-r-3-phenyl-3-4-trifluoromethyl-phenoxy-propyl-amino-acetic acid
5311285
2-[methyl-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amino]acetic acid
CN(CCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F)CC(=O)O
This item is not returnable. View return policy
372198-97-5
C19H20F3NO3
367.368
KZWQAWBTWNPFPW-QGZVFWFLSA-N
2-methyl-3r-3-phenyl-3-4-trifluoromethyl phenoxy propyl amino acetic acid, d00lnk, n-methyl-n-3r-3-phenyl-3-4-trifluoromethyl phenoxy propyl-glycine, methyl-r-3-phenyl-3-4-trifluoromethyl-phenoxy-propyl-amino-acetic acid
5311285
2-[methyl-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amino]acetic acid
CN(CCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F)CC(=O)O

Inhibitor of GlyT1; derivative of Org 24598 (Cat. No. 4035).

Potent and selective inhibitor of the glial glycine transporter GlyT1b (IC50 = 6.9 nM). Displays negligible activity at GlyT-2, adrenoreceptors, dopamine, 5HT receptors and noradrenaline, dopamine, 5HT and GABA transporters (pIC50 < 4). Active in vivo.
Linear Formula C19H20F3NO3
Quantity 10 mg
Solubility Information Soluble to 10mM in water with gentle warming and to 100mM in DMSO
Formula Weight 367.36
Chemical Name or Material N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-glycine
Grade >98%
Recommended Storage Store at +4°C
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