OSGEP Mouse anti-Human, Clone: OTI8B3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525566
DescriptionOsgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Probable tRNA N6-adenosine threonylcarbamoyltransferaseUniRule annotation; N6-L-threonylcarbamoyladenine synthase; t(6)A synthase; O-sialoglycoprotein endopeptidaseUniRule annotation; hOSGEP; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; OSGEP; GCPL1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 1-335 of OSGEP produced in E.coli|
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