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Osteopontin Rabbit anti-Human, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 229521AP

Catalog No. 50-173-3972


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Description

Description

Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in maligt glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.
Specifications

Specifications

Osteopontin
0.36 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P08721, P10451
BNSP, Bone sialoprotein 1, BSPI, ETA 1, Nephropontin, OPN, Osteopontin, secreted phosphoprotein 1, SPP 1, SPP1, Urinary stone protein, Uropontin
Rabbit
IgG
150 μL
-20°C
Primary
25353, 6696
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
SPP1
Liquid
SPP1
Osteopontin Fusion Protein Ag19216
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Rat
Documents
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