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  8. p-Toluenesulfonyl isocyanate, 95%, Thermo Scientific Chemicals

p-Toluenesulfonyl isocyanate, 95%, Thermo Scientific Chemicals

Catalog Number aaa1749214
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Quantity:
25 g
100 g
500 g
4083-64-1
C8H7NO3S
197.21
MFCD00002030
VLJQDHDVZJXNQL-UHFFFAOYSA-N
tosyl isocyanate, p-toluenesulfonyl isocyanate, 4-methylbenzenesulfonyl isocyanate, p-toluenesulphonyl isocyanate, benzenesulfonyl isocyanate, 4-methyl, tosylisocyanate, p-tolylsulfonyl isocyanate, unii-h9004fjx6v, p-toluenesulfonic acid, anhydride with isocyanic acid, p-toluene sulfonyl isocyanate
77703
4-methyl-N-(oxomethylidene)benzenesulfonamide
CC1=CC=C(C=C1)S(=O)(=O)N=C=O
4083-64-1
C8H7NO3S
197.21
MFCD00002030
VLJQDHDVZJXNQL-UHFFFAOYSA-N
tosyl isocyanate, p-toluenesulfonyl isocyanate, 4-methylbenzenesulfonyl isocyanate, p-toluenesulphonyl isocyanate, benzenesulfonyl isocyanate, 4-methyl, tosylisocyanate, p-tolylsulfonyl isocyanate, unii-h9004fjx6v, p-toluenesulfonic acid, anhydride with isocyanic acid, p-toluene sulfonyl isocyanate
77703
4-methyl-N-(oxomethylidene)benzenesulfonamide
CC1=CC=C(C=C1)S(=O)(=O)N=C=O

Description

It is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides. -Toluenesulfonyl isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS. It is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides. -Toluenesulfonyl isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS. It is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.

Solubility
Reacts with water.

Notes
Keep away from alcohols, strong bases, amines, strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Melting Point 5°C
Density 1.295
Boiling Point 144°C (10 mmHg)
Flash Point 145°C (293°F)
Odor Irritating
Refractive Index 1.535
Quantity 25 g
UN Number UN2206
Beilstein 391287
Sensitivity Moisture sensitive
Solubility Information Reacts with water.
Formula Weight 197.21
Percent Purity 95%
Chemical Name or Material p-Toluenesulfonyl isocyanate
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Safety and Handling

Hazard Category H315-H319-H334-H335-H336
Hazard Statement GHS H Statement
H334-H335-H315-H319
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Causes serious eye irritation.
Precautionary Statement P261-P264b-P271-P280-P285-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P331-P332+P313-P342+P311-P362-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: ISOCYANATES, TOXIC, N.O.S.
EINECSNumber 223-810-8
RTECSNumber DB9032000
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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