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P005091, Tocris Bioscience™

Catalog Number 473310
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
882257-11-6
C12H7Cl2NO3S2
348.21
MFCD00123202
LKZLGMAAKNEGCH-UHFFFAOYSA-N
1-5-2,3-dichlorophenylthio-4-nitrothiophen-2-yl ethanone, 1-5-2,3-dichloro-phenylsulfanyl-4-nitro-thiophen-2-yl-ethanone, 1-5-2,3-dichlorophenyl thio-4-nitro-2-thienyl ethanone, 1-5-2,3-dichlorophenyl sulfanyl-4-nitrothiophen-2-yl ethanone, cyto5d7, 1-5-2,3-dichlorophenyl sulfanyl-4-nitro-2-thienyl ethanone, 1-5-2,3-dichlorophenylsulfanyl-4-nitro-2-thienyl ethanone, 1-5-2,3-dichlorophenyl thio-4-n?itro-2-thienyl ethanone, 1-5-2,3-dichlorophenyl sulfanyl-4-nitrothiophen-2-yl ethan-1-one
2819993
1-{5-[(2,3-dichlorophenyl)sulfanyl]-4-nitrothiophen-2-yl}ethan-1-one
CC(=O)C1=CC(=C(SC2=C(Cl)C(Cl)=CC=C2)S1)[N+]([O-])=O
This item is not returnable. View return policy
882257-11-6
C12H7Cl2NO3S2
348.21
MFCD00123202
LKZLGMAAKNEGCH-UHFFFAOYSA-N
1-5-2,3-dichlorophenylthio-4-nitrothiophen-2-yl ethanone, 1-5-2,3-dichloro-phenylsulfanyl-4-nitro-thiophen-2-yl-ethanone, 1-5-2,3-dichlorophenyl thio-4-nitro-2-thienyl ethanone, 1-5-2,3-dichlorophenyl sulfanyl-4-nitrothiophen-2-yl ethanone, cyto5d7, 1-5-2,3-dichlorophenyl sulfanyl-4-nitro-2-thienyl ethanone, 1-5-2,3-dichlorophenylsulfanyl-4-nitro-2-thienyl ethanone, 1-5-2,3-dichlorophenyl thio-4-n?itro-2-thienyl ethanone, 1-5-2,3-dichlorophenyl sulfanyl-4-nitrothiophen-2-yl ethan-1-one
2819993
1-{5-[(2,3-dichlorophenyl)sulfanyl]-4-nitrothiophen-2-yl}ethan-1-one
CC(=O)C1=CC(=C(SC2=C(Cl)C(Cl)=CC=C2)S1)[N+]([O-])=O

USP7 inhibitor

Selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2 μM). Displays little-to-no inhibition of other USP variants or proteases such as caspase, cathepsins and serine proteases; exhibits some activity at USP47. Induces elevated p53 and apoptosis in cancer cell lines; displays antiangiogenic activity in vivo.
Quantity 10 mg
Formula Weight 348.22
Percent Purity >99%
Chemical Name or Material P005091
Recommended Storage Store at +4°C
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