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P005091, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
882257-11-6
C12H7Cl2NO3S2
348.212
LKZLGMAAKNEGCH-UHFFFAOYSA-N
1-5-2,3-dichlorophenylthio-4-nitrothiophen-2-yl ethanone,1-5-2,3-dichloro-phenylsulfanyl-4-nitro-thiophen-2-yl-ethanone,1-5-2,3-dichlorophenyl thio-4-nitro-2-thienyl ethanone,1-5-2,3-dichlorophenyl sulfanyl-4-nitrothiophen-2-yl ethanone,cyto5d7,1-5-2,3-dichlorophenyl sulfanyl-4-nitro-2-thienyl ethanone,1-5-2,3-dichlorophenylsulfanyl-4-nitro-2-thienyl ethanone,1-5-2,3-dichlorophenyl thio-4-n?itro-2-thienyl ethanone,1-5-2,3-dichlorophenyl sulfanyl-4-nitrothiophen-2-yl ethan-1-one
2819993
1-[5-(2,3-dichlorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone
CC(=O)C1=CC(=C(S1)SC2=C(C(=CC=C2)Cl)Cl)[N+](=O)[O-]
This item is not returnable. View return policy
882257-11-6
C12H7Cl2NO3S2
348.212
LKZLGMAAKNEGCH-UHFFFAOYSA-N
1-5-2,3-dichlorophenylthio-4-nitrothiophen-2-yl ethanone,1-5-2,3-dichloro-phenylsulfanyl-4-nitro-thiophen-2-yl-ethanone,1-5-2,3-dichlorophenyl thio-4-nitro-2-thienyl ethanone,1-5-2,3-dichlorophenyl sulfanyl-4-nitrothiophen-2-yl ethanone,cyto5d7,1-5-2,3-dichlorophenyl sulfanyl-4-nitro-2-thienyl ethanone,1-5-2,3-dichlorophenylsulfanyl-4-nitro-2-thienyl ethanone,1-5-2,3-dichlorophenyl thio-4-n?itro-2-thienyl ethanone,1-5-2,3-dichlorophenyl sulfanyl-4-nitrothiophen-2-yl ethan-1-one
2819993
1-[5-(2,3-dichlorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone
CC(=O)C1=CC(=C(S1)SC2=C(C(=CC=C2)Cl)Cl)[N+](=O)[O-]

USP7 inhibitor

Selective inhibitor of ubiquitin-specific protease (USP) 7 (IC50 = 4.2 μM). Displays little-to-no inhibition of other USP variants or proteases such as caspase, cathepsins and serine proteases; exhibits some activity at USP47. Induces elevated p53 and apoptosis in cancer cell lines; displays antiangiogenic activity in vivo.

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Quantity 50mg
Formula Weight 348.22
Percent Purity >99%
Chemical Name or Material P005091

Recommended Storage : Store at +4°C