Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thermo Scientific™ Lab Vision™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody.

Specifications

Antigen p130/Rb2 Ab-2
Clone 130P215; same as DCS-215
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Conjugate Unconjugated
View More Specs

Products 1
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS866R1
View Documents
Thermo Scientific™
MS866R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ p130/Rb2 Ab-2, Mouse Monoclonal Antibody.

Two retinoblastoma-related proteins, p107 and pRb2/p130 are structurally and functionally similar to the product of the retinoblastoma gene (pRb/p105). Like pRb they bind transforming proteins of DNA tumor viruses through a particular region called the “pocket domain”. Both proteins play a fundamental role in growth control. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2/p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer.

Host Species: Mouse

Clone: 130P215; same as DCS-215

Isotype: IgG1

Species Reactivity: Human and Rat. Others not known.

Epitope: aa 878-913

Immunogen: A synthetic peptide from p130 corresponding to aa 878-913

Molecular Weight: 130kDa

Positive Control: A427 cells, Tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

p130/Rb2 Ab-2
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RUO
Primary
IgG1
130P215; same as DCS-215
Monoclonal
Murine
Cell Cycle
A synthetic peptide from p130 corresponding to aa878-913
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit