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P2X6 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548819

Catalog No. PA548819

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

P2rx6 encodes receptors that are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each P2rx6 receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains. The protein encoded by the P2rx6 gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. The P2rx6 gene is predomitly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants of P2rx6.
Specifications

Specifications

P2X6
Polyclonal
PBS with 0.09% sodium azide
O15547
P2X purinoceptor 6, P2X6, ATP receptor, P2XM, Purinergic receptor, Purinergic receptor P2X-like 1, P2RX6, P2RXL1, P2X6
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
9127
Western Blot
Unconjugated
P2RX6
Liquid
P2RX6
KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human P2RX6.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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