Invitrogen™ p400 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530780

Catalog No. PIPA530780

Description

Recommended positive controls: MCF-7. Predicted reactivity: Mouse (83%), Rat (82%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.

Specifications

• Antigen: p400
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EP400
• Gene Alias: 1700020J09Rik; AU023439; CAG repeat protein 32; CAGH32; Domino homolog; E1A binding protein p400; E1A-binding protein p400; EP400; hDomino; KIAA1498; KIAA1818; mDomino; mKIAA1498; P400; p400 kDa SWI2/SNF2-related protein; p400 SWI2/SNF2-related protein; TNRC12; trinucleotide repeat containing 12; trinucleotide repeat-containing gene 12 protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57634
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.95 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96L91
• Gene Symbols: EP400
• Immunogen: Recombinant fragment corresponding to a region within amino acids 136 and 430 of Human p400.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG