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P4HA2 Mouse anti-Human, Clone: CL0351, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524599

Catalog No. PIMA524599


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Description

Description

Immunogen sequence: LKEYILVEEA KLSKIKSWAN KMEALTSKSA ADAEGYLAHP VNAYKLVKRL NTDWPALEDL VLQDSAAGFI ANLSVQRQFF PTDEDEIGAA KALMRLQDTY RLDPGTISRG ELPGTKYQAM LSVDDCFGM Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 91%. Binds to an epitope located within the peptide sequence NTDWPALEDLVLQDS as determined by overlapping synthetic peptides.

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Specifications

Specifications

P4HA2
Monoclonal
1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
O15460
4-PH alpha 2, 4-PH alpha-2, C-P4Halpha(II), collagen prolyl 4-hydroxylase alpha(II), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II, procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2, prolyl 4-hydr
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
8974
Immunohistochemistry, Western Blot
CL0351
Unconjugated
P4HA2
Liquid
P4HA2
Recombit protein corresponding to Human P4HA2
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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