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Thermo Scientific™ Lab Vision™ p53 Ab-6, Mouse Monoclonal Antibody

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-6, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ MS187P

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Catalog No. MS187P


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Description

Description

Achieve accurate, reproducible results with the Thermo Scientific™ p53 Ab-6, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-1

Isotype: IgG2a

Species Reactivity: Human, Monkey and Cow. Reacts weakly with Mouse and Rat. Others not known.

Epitope: aa 11-25

Immunogen: Recombinant human wild-type p53 protein expressed in E. coli

Molecular Weight: 53kDa

Positive Control: SKBR-3 cells or MDA-231 cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry
  • Gel Supershift Assay

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

p53 Ab-6
Monoclonal
200μg/mL
Purified Ab with BSA and Azide
Murine
IgG2a
RUO
Primary
Monoclonal
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
DO-1
Unconjugated
Concentrated
Recombinant human wild-type p53 protein expressed in E. coli
1mL
Cell Cycle
Primary
Bovine, Human, Non-human Primate
SDS
Documents
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