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Thermo Scientific™ Lab Vision™ p53 Ab-8, Mouse Monoclonal Antibody

Deliver accurate, reproducible results with the Thermo Scientific™ p53 Ab-8, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ MS738P

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Catalog No. MS738P


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Description

Description

Deliver accurate, reproducible results with the Thermo Scientific™ p53 Ab-8, Mouse Monoclonal Antibody.

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-7 + BP53-12

Isotype: IgG2b + IgG2a

Species Reactivity: Human. Others not known.

Epitope: aa 37-45 and aa 20-25

Immunogen: Recombinant human p53 protein

Molecular Weight: 53kDa

Positive Control: MDA-231, SKBR-3 cells or Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native and denatured)
Specifications

Specifications

p53 Ab-8
Monoclonal
200μg/mL
Purified Ab with BSA and Azide
Murine
IgG2a IgG2b
IVD
Primary
Monoclonal
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
DO-7 + BP53-12
Unconjugated
Concentrated
Recombinant human p53 protein
1mL
Cancer and Tumor Biology
Primary
Human
SDS
Documents
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