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Epredia™ Lab Vision™ p53 Rabbit Monoclonal Antibody (Clone SP5)
Employ part of a comprehensive antibody portfolio with the Epredia™ p53, Rabbit Monoclonal Antibody (Clone SP5). Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.
Supplier: Epredia™ RM9105S1
Description
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Host Species: Rabbit
Clone: SP5
Isotype: IgG
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Recombinant human full-length wild type p53 protein
Molecular Weight: 53kDa
Positive Control: MDA-231 cells, Colon CA
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
Specifications
| p53 | |
| Monoclonal | |
| Unconjugated | |
| Recombinant human full-length wild type p53 protein | |
| IVD | |
| Primary | |
| Concentrated |
| Western Blot | |
| SP5 | |
| Rabbit | |
| 500 μL | |
| Cancer and Tumor Biology | |
| Human | |
| IgG |
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