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p57Kip2Ab-6 Mouse Monoclonal Antibody, Epredia™
Deliver accurate, reproducible results with the Epredia™ p57Kip2 Ab-6, Mouse Monoclonal Antibody.
$318.00 - $1470.00
Specifications
Antigen | p57superscriptKip2superscript Ab-6 |
---|---|
Applications | Immunohistochemistry (Paraffin), Immunoprecipitation |
Classification | Monoclonal |
Conjugate | Unconjugated |
Host Species | Mouse |
Catalog Number | Mfr. No. | Form | Quantity | Price | Quantity & Availability | ||||
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Catalog Number | Mfr. No. | Form | Quantity | Price | Quantity & Availability | ||||
MS1062P0
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Epredia
MS1062P0 |
Concentrated | 100 μL |
Each for $318.00
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MS1062PABX
|
Epredia
MS1062PABX |
Concentrated | 200 μL |
Each for $1,142.00
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MS1062P1
|
Epredia
MS1062P1 |
Concentrated | 500 μL |
Each for $863.00
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MS1062P
|
Epredia
MS1062P |
Concentrated | 1 mL |
Each for $1,470.00
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MS1062R7
|
Epredia
MS1062R7 |
Prediluted | 7 mL |
Each for $874.00
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MS1062P1ABX
|
Epredia
MS1062P1ABX |
Concentrated | 100 μL | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | ||||
MS1062R1
|
Epredia
MS1062R1 |
Prediluted | 1 mL | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | ||||
MS1062RQ
|
Epredia
MS1062RQ |
Ready-to-Use | 12 mL | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | ||||
Description
p57Kip2 (or CDKN1C) is a potent tight-binding inhibitor of several G1 cyclin complexes, and is a negative regulator of cell proliferation. The gene encoding human p57Kip2 is located on chromosome 11p15.5, a region implicated in both sporadic cancers, Wilm's tumor, and Beckwith-Wiedemann syndrome (BWS), a cancer syndrome, making it a tumor suppressor candidate. BWS is characterized by numerous growth abnormalities and an increased risk of childhood tumors. Several types of childhood tumors including Wilms' tumor, adrenocortical carcinoma and rhabdomyosarcoma display a specific loss of maternal 11p15 alleles, suggesting that genomic imprinting plays an important part. This region also contains two other imprinted genes, insulin-like growth factor II (IGF-II) and H19, both of which seem to be implicated in adrenal neoplasms.Host Species: Mouse
Clone: 57P06; same as KP10
Isotype: IgG2b/κ
Species Reactivity: Human and Mouse. Others not known.
Epitope: Not determined
Immunogen: Recombinant human p57Kip2 protein
Molecular Weight: 57kDa
Positive Control: LS174T cells, Colon CA or placenta
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting (Not suitable)
- Immunoprecipitation (Native verified)
Specifications
p57superscriptKip2superscript Ab-6 | |
Monoclonal | |
Mouse | |
Cell Cycle | |
Primary |
Immunohistochemistry (Paraffin), Immunoprecipitation | |
Unconjugated | |
IVD | |
Recombinant human p57superscriptKip2superscript protein |
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