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p73 Mouse anti-Human, Mouse, Rat, Alexa Fluor™ 750, Clone: 5B429, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP224737AF750

Catalog No. NP224737A70


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Description

Description

p73 Monoclonal antibody specifically detects p73 in Human,Mouse,Rat samples. It is validated for Western Blot,Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin),Immunohistochemistry (Frozen).
Specifications

Specifications

p73
5B429
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Intracellular)
p53-related protein, P73p53-like transcription factor, TA p73, TAp73, tumor protein p73
Mouse
IgG1 Kappa
Store at 4°C in the dark.
Monoclonal
p73 antibody (clone 5B429) recognizes all of the TAp73 isoforms i.e. isoforms with an intact NH2-terminal transactivation domain (Thottassery et el, 2006, PMID 16505115). Sayan et al 2005 (PMID 15781249) showed that p73 IMG-246/ NBP2-24737 reacted with all tested TAp73 isoforms but not deltaNp73 whereas p73 antibody clone 5B1288 (NB100-56674/ IMG-259A ) showed reactivity against all p73 isoforms including delta Np73. Caspase-cleaved p73 fragments, including 55 kDa and 45 kDa, have been described in literature (Sayan et al, 2008). p73 antibody clone 5B429 has also been referred to as 429 in the literature.
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Alexa Fluor™ 750
50 mM sodium borate with 0.05% sodium azide
TP73
This antibody was raised against full-length human p73. It reacts with an epitope that is located on the N-terminal region of human p73. It does not cross react with p53.
0.1 mL
Primary
7161
Human, Mouse, Rat
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