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Tocris Bioscience™ PA 1 dihydrochloride

Photoswitchable ENaC blocker

$209.00 - $879.00

Specifications

Chemical Name or Material 3,5-Diamino-6-chloro-N-[imino[[4-(2-phenyldiazenyl)phenyl]amino]methyl]-2-pyrazinecarboxamide dihydrochloride
Molecular Formula C18H16ClN9O.2HCl
Product Type Target: Ion Channel Modulators
Formula Weight 482.75
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
546310 View Documents Tocris Bioscience™
5463/10
10mg Each for $209.00
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546350 View Documents Tocris Bioscience™
5463/50
50mg Each for $879.00
Add to cart
 
Description

Description

Photoswitchable epithelial sodium channel (ENaC) blocker (IC50 values are 90 and 390 nM for αβγ and δβγENaCs, respectively, in the trans conformation). Switches conformation from cis to trans at 500 nm and trans to cis at 400 nm. Blocks ENaCs with greater efficacy in the cis conformation, in comparison to the trans conformation, in Xenopus oocytes and HEK293t cells. Partially blocks δβγENaCs in the trans conformation and exhibits near maximal block of δβγENaCs in the cis conformation. Amiloride derivative.
Specifications

Specifications

3,5-Diamino-6-chloro-N-[imino[[4-(2-phenyldiazenyl)phenyl]amino]methyl]-2-pyrazinecarboxamide dihydrochloride
C18H16ClN9O.2HCl
Target: Ion Channel Modulators
482.75
Safety and Handling

Safety and Handling

Recommended Storage : Store at −20°C

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