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Tocris™ PA 452

RXR antagonist

Manufacturer:  Tocris™ 5086/10

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Catalog No. 50-861-0

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For Research Use Only



RXR antagonist (pA2 = 7.11). Triggers dissociation of RXR tetramers. Attenuates cell proliferation and induces apoptosis in MCF-7 breast cancer cells.
  • Chemical Name: 2-[[3-(Hexyloxy)-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl]methylamino]-5-pyrimidinecarboxylic acid
  • Formula: C26H37N3O3
  • CAS Number: 457657-34-0
  • Solubility: Soluble to 100mM in DMSO and to 10mM in ethanol
  • Purity: >98
Description & Specifications


PA 452
PA 452
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