PAAF1 Mouse anti-Human, Mouse, Clone: OTI1F11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526327
DescriptionPAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|PAAF, Rpn14, WDR71, WD repeat domain 71, WD repeat-containing protein 71|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Full length human recombit protein of PAAF1 produced in HEK293T cell|
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