PACSIN2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA141564

Catalog No. 01-675-183

Description

This antibody is predicted to react with mouse, rat, canine, bovine, and chicken based on sequence homology.

PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.

Specifications

• Antigen: PACSIN2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PACSIN2
• Gene Alias: AI197433; cytoplasmic phosphoprotein PACSIN2; Pacsin2; pacsin2.S; protein kinase C and casein kinase substrate in neurons 2; protein kinase C and casein kinase substrate in neurons 2 protein; protein kinase C and casein kinase substrate in neurons 2 S homeolog; protein kinase C and casein kinase substrate in neurons protein 2; RP3-437M21.1; SdpII; SdpIIsyndapin II; synaptic dynamin-associated protein II; syndapin 2; Syndapin II; syndapin2; syndapin-2; Syndapin-II; XELAEV_18019736mg; x-PACSIN2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11252, 124461, 23970, 398138
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.2% gelatin and 0.05% sodium azide
• Gene Accession No.: Q9DDA9, Q9QY17, Q9UNF0, Q9WVE8
• Gene Symbols: PACSIN2, pacsin2.S
• Immunogen: Synthetic peptide corresponding to residues 400-450 of human PACSIN 2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat, X. laevis
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov