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PACSIN3 Mouse anti-Canine, Human, Non-human primate, Rat, Clone: OTI4G7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525367

Catalog No. PIMA525367


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Description

Description

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Specifications

Specifications

PACSIN3
Monoclonal
0.6 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9UKS6
PACSIN3; protein kinase C and casein kinase substrate in neurons 3; SH3 domain-containing protein 6511; SDPIII; syndapin III; SH3 domain-containing protein 6511
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
29763, 311187, 475984, 713919
Flow Cytometry, Western Blot
OTI4G7
Unconjugated
PACSIN3
Liquid
PACSIN3
Full length human recombit protein of PACSIN3 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Non-human primate, Rat
Documents
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