Invitrogen™ PAK1IP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530660

Catalog No. PIPA530660

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (81%), Rat (89%), Chicken (80%), Rhesus Monkey (100%), Bovine (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868). [UniProt].

Specifications

• Antigen: PAK1IP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAK1IP1
• Gene Alias: 5830431I15Rik; 5930415H02Rik; AA419825; AI314040; AW556169; bA421M1.5; Gdpd1; glycerophosphodiester phosphodiesterase domain containing 1; hPIP1; MAK11; p21-activated protein kinase-interacting protein 1; PAK/PLC-interacting protein 1; PAK1 interacting protein 1; PAK1-interacting protein 1; PAK1IP1; PIP1; putative PAK inhibitor Skb15; RP11-421M1.5; WD repeat-containing protein 84; WDR84
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55003
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M Tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9NWT1
• Gene Symbols: PAK1IP1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 8 and 226 of Human PAK1 interacting protein 1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG